||Changing-look quasars are a recently identified class of active galaxies in which the strong UV continuum and/or broad optical hydrogen emission lines associated with unobscured quasars either appear or disappear on time-scales of months to years. The physical processes responsible for this behaviour are still debated, but changes in the black hole accretion rate or accretion disc structure appear more likely than changes in obscuration. Here, we report on four epochs of spectroscopy of SDSS J110057.70-005304.5, a quasar at a redshift of z = 0.378 whose UV continuum and broad hydrogen emission lines have faded, and then returned over the past approximate to 20 yr. The change in this quasar was initially identified in the infrared, and an archival spectrum from 2010 shows an intermediate phase of the transition during which the flux below rest frame approximate to 3400 angstrom has decreased by close to an order of magnitude. This combination is unique compared to previously published examples of changing-look quasars, and is best explained by dramatic changes in the innermost regions of the accretion disc. The optical continuum has been rising since mid-2016, leading to a prediction of a rise in hydrogen emission-line flux in the next year. Increases in the infrared flux are beginning to follow, delayed by a similar to 3 yr observed time-scale. If our model is confirmed, the physics of changing-look quasars are governed by processes at the innermost stable circular orbit around the black hole, and the structure of the innermost disc. The easily identifiable and monitored changing-look quasars would then provide a new probe and laboratory of the nuclear central engine.